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ProFeme® Progesterone Cream

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Progesterone Cream for Women - Quick Q & A

ProFeme Progesterone Cream

What is meant by the term bioidentical hormones?

A. The term bioidentical hormones refers to the identical hormones to that produced naturally by the ovaries in women and the testes in men. The bioidentical hormone progesterone has the exact chemical finger print as that which is made by the human ovaries. Many pharmaceutical hormones are not bioidentical hormones, but rather synthetic analogues which may have similar actions as bioidentical hormones. In the case of synthetic progestins (progesterone analogues) they are do not have the wide spectrum of action as bioidentical progesterone, they are usually stronger and have beneficial actions limited to the uterine lining, they have unwanted side effects compared to the bioidentical hormone progesterone and are patented.

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Is the progesterone in ProFeme® "natural®" progesterone?

A. Yes. ProFeme® Progesterone Cream is guaranteed 100% to contain "natural" progesterone. Natural progesterone was the term coined by US doctor John Lee MD to differentiate between the chemical structure of progesterone produced by the ovaries ("natural") and the chemical structures of the synthetically produced progestins which are often confused as being progesterone. Their chemical fingerprint is totally different and natural progesterone has a far greater diversity of action than progestins.

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Does the wild yam contain natural progesterone?

A. No - definitely not. The wild yam contains a steroid substrate called diosgenin that is similar in its chemical structure to progesterone. Diosgenin however does not act like progesterone within the body. The human body is unable to convert diosgenin into progesterone - a point often misrepresented by marketers of wild yam products.

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Where does "natural" progesterone come from?

A. Wild yam and soya are the two crops which contain steroid substrate (diosgenin and sigmasterol - plant hormones) similar in their chemical structure to progesterone. Because these two crops are grown in commercial quantities large quantities of raw substrate material can be extracted. Diosgenin and sigmasterol are converted in a laboratory to make "natural" progesterone. This is the same chemical structure as produced by the ovaries and is identical in every way.

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Is the progesterone in ProFeme® Progesterone Cream made from genetically modified soya?

A. No - Lawley Pharmaceuticals in Australia, the manufacturers of ProFeme®, has documentation from the raw material manufacturers that the progesterone is not produced from genetically engineered soya crops.

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Why is ProFeme® Progesterone Cream superior to other progesterone cream brands?

A. ProFeme® Progesterone Cream is manufactured to pharmaceutical grade standards whereas in the USA over-the-counter progesterone creams are made to cosmetic grade standards. The requirement for labelling disclosure of the amount of progesterone in the finished product is optional. Many products available in the US for example may claim to have progesterone in the finished product, but in fact can have little or no progesterone. Because ProFeme® has much stricter standards of manufacture the amount stated on the label is guaranteed to be what is in the finished product. Additionally ProFeme® Progesterone Cream has undergone comprehensive raw material purity testing, clinical trials and stability testing. The quality difference between ProFeme® Progesterone Cream and other cosmetic brands is significant.

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How long before ProFeme® Progesterone Cream helps my PMS or menopausal symptoms?

A. Usually it takes between 4 and 8 weeks for ProFeme® to reverse symptoms. Many people want an overnight cure to their menopausal problems or PMS symptoms. It must be remembered that the underlying hormone imbalance that lead to the point where symptoms warranted treatment usually developed over many months, if not years. They cannot be reversed overnight. Most people find that symptoms improve steadily with each month of use. After about 12 months use maximum effect is achieved.

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Do I need a doctor's prescription for ProFeme® Progesterone Cream in the USA?

A. No, progesterone cream is available without prescription in the USA. If ProFeme® Progesterone Cream is being used to assist with fertility or treat more severe gynecological conditions such as endometriosis or Polycystic Ovarian Syndrome, it is strongly recommended that treatment be undertaken under medical supervision.

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  • Progesterone Use in Women